Physically, not really. There’s a small chance you could vomit. Because of this risk it’s always good Flamingo adios school hello pool paralife life shirt to have a trip-sitter around to make sure you don’t get hurt or die on your vomit. You may also want to sit up in a relaxed position, or roll onto your side. This advice really goes for all drugs that can knock you out, from alcohol to ketamine to benzos. Mentally, kind of sort of not really. It’s dangerous for the structures of modern society itself, much like the other psychedelics. It will make you question reality, god(s), your own mental well-being and life-choices. DMT has no known toxic dosage but like even water, too much of anything will eventually kill you. So don’t be stupid with your dosing! Especially if you bought it and don’t know how clean it is.
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DMT may not be known to be toxic but non-evaporated solvents sure are! But keep in mind the dangers of DMT are not limited to Flamingo adios school hello pool paralife life shirt itself. It’s route of administration can be potentially lethal if using an MAOI with common western anti-depressants and ADHD stimulants. More details on that in the question below. Just like other psychedelics there is a chance of experiencing a very rough trip, often called a bad trip. DMT and other psychedelics can be traumatizing. The come-up can also be terrifying if someone has never experienced breathing difficulties before. The middling doses feel like you’ve been poisoned or something. I don’t want to over-emphasize these negative aspects because I think they’re overblown and completely neglects all potential benefits that occurred regardless. However I see enough posts about people having freak outs to know it happens often enough. I don’t think people with cowardly dispositions should mess with something as powerful as DMT unless they feel they need it. It can be a very scary experience, it’s just usually not scary once the come-up is over.