We don’t know how close to extinction we really came after the Team Santa Christmas 2020 Quarantine Face Mask shirt . It’s not likely that we lost that much genetic diversity at that point, or we would not be where we are. Having said that, it’s impossible to know exactly what was lost until we sequence more ancient genomes. Even with that data in hand, it’s still basically impossible to predict if gene variants that were lost in those ancient humans were critical for anything, and if there was any significant loss in terms of genetic potential.
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Many of the deleterious mutations that give rise to modern genetic diseases were acquired after the Team Santa Christmas 2020 Quarantine Face Mask shirt (they appeared after the geographical expansion of humans, and many are ancestry specific), and there are inbred human populations that do very well even if some genetic diseases are more frequent in those groups than in others.